Depression Treatment in Fort Worth
Medically reviewed by Diana Ghelber, MD · Updated October 25, 2026
Whether you are seeking help for the first time or looking for another approach after previous treatment, we begin by listening.
The Institute for Advanced Psychiatry offers comprehensive psychiatric evaluations and medication management in Fort Worth, with a particular focus on Deep TMS, IV ketamine, and other interventional approaches. We also discuss PRISM EEG-based neurofeedback for anhedonia when appropriate.
IV ketamine for depression is used off-label. PRISM for anhedonia is investigational.
Depression affects more than mood
Depression can affect energy, sleep, concentration, appetite, relationships, and daily functioning. Some people experience persistent sadness; others feel numb, irritable, or disconnected.
Anhedonia—a reduced ability to experience interest or pleasure—can be particularly difficult. An evaluation helps us understand these symptoms alongside anxiety, trauma, substance use, pain, sleep problems, or medical conditions.
If your mood changes as the days grow shorter, read When the Days Grow Darker: Light Therapy for Seasonal Affective Disorder, a reflection from Dr. Ghelber on seasonal depression and light therapy.
Treatment options
Psychiatric evaluation and medication management
We review your concerns, treatment history, current medications, medical conditions, and goals. Medication may be an appropriate first step or part of a broader plan. We monitor response and side effects and adjust treatment when needed.
Deep TMS
Our practice uses the BrainsWay Deep TMS system. Treatment uses magnetic pulses while you are awake and does not require anesthesia. We assess suitability and safety before recommending it.
TMS does not need to be the last option discussed after years of unsuccessful treatment. Previous antidepressant treatment, the applicable device indication, and individual clinical circumstances guide eligibility.
IV ketamine
For selected patients, IV ketamine may be considered following an evaluation. Some patients experience improvement relatively quickly, sometimes within the first day after an infusion. Not everyone responds, and the duration of improvement varies. We discuss risks, monitoring, alternatives, and follow-up. Its use for depression is off-label.
Explore IV ketamine treatment · When might TMS and ketamine both be considered?
PRISM for anhedonia
If loss of interest or pleasure is a central concern, ask about PRISM EEG-based neurofeedback. Its use for anhedonia is investigational. We explain the available evidence, uncertainties, and other options.
Learn about PRISM neurofeedback
How we choose treatment together
We consider your diagnosis, symptom severity, prior treatment response, medical conditions, preferences, and the practical demands of care. Treatments have different risks and requirements; adding more treatments is not automatically better.
Our goal is remission whenever possible, together with improved functioning and a plan to maintain progress. We assess how you are feeling and what you are becoming able to do again.
If depression has persisted despite previous treatment, learn more about our approach to treatment-resistant depression.
Read about depression and physical health
Clinical experience informed by research
Led by board-certified psychiatrist Diana Ghelber, MD, our team provides individualized psychiatric care. Dr. Ghelber is a coauthor of multicenter studies of Deep TMS outcomes in everyday clinical settings:
These studies contribute to our understanding of treatment; they do not predict an individual outcome or establish eligibility for every age studied.
Selected Conference Abstracts
- Ghelber D, Thomas AT, Prater EL, Yang C. Increasing Number of dTMS Sessions Improves Response Rate in Major Depression. Transcranial Magnetic Stimulation. 2024;1:100026.
- Brainsway™ dTMS (TMS) and Brainsway™ dTMS with Ketamine Infusions (TMSK) in Treatment-Resistant Depression (TRD); Real life results — Diana Ghelber and Kumud Khanal. Published abstract, Brain Stimulation. 2018;11(6).
This small observational study compared Deep TMS with and without ketamine infusions. It did not establish that adding ketamine was superior to Deep TMS alone.
These conference abstracts describe observational clinical findings and should not be interpreted as predicting an individual patient’s response to treatment.
Supporting your existing psychotherapy
If you already work with a therapist, we can coordinate with your permission. Psychiatric care may help address symptoms that make it difficult to participate fully in that ongoing work.
Feeling stuck in therapy? Depression may be part of the picture.
Request a depression evaluation
We can help you understand your options and the next steps. Call 817-659-7344 or request an appointment online.
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Our outpatient practice does not provide emergency psychiatric services. If you are in immediate danger or may harm yourself or someone else, call 911 or go to the nearest emergency department.
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